abstract：:Bovine hemoglobin (Hb) was encapsulated inside polymer vesicles (polymersomes) to form polymersome encapsulated Hb (PEH) dispersions. PEH particles are 100% surface PEGylated with longer PEG chains and possess thicker hydrophobic membranes as compared to conventional liposomes. Polymersomes were self-assembled from po...

journal_title：Biomacromolecules

authors： Arifin DR,Palmer AF

更新日期：2005-07-01 00:00:00

abstract：:Combining molecular weight distribution (MWD) data for linear chains of debranched starch from capillary electrophoresis and from size exclusion chromatography (SEC) with detection by differential refractive index and by multi-angle laser light scattering has enabled Mark-Houwink parameters to be determined for linear...

journal_title：Biomacromolecules

authors： Castro JV,Ward RM,Gilbert RG,Fitzgerald MA

更新日期：2005-07-01 00:00:00

abstract：:New type of N-glycosylated peptides having periodic sequence of -[X-Gln(beta-D-GlcNAc)-Aib]- [X = L-Glu(OMe), L-Lys(Ac), L-Ala; Aib = alpha-aminoisobutyric acid] were synthesized by polymerization of glycosylated tripeptides with an active ester methods using Cl(-+)H(3)N-L-Glu(OMe)-Gln[beta-D-GlcNAc(Ac)(3)]-Aib-ONp (N...

journal_title：Biomacromolecules

authors： Takasu A,Horikoshi S,Hirabayashi T

更新日期：2005-07-01 00:00:00

abstract：:The objective of this study was to explore the use of reverse thermo-responsive (RTG) polymers for generating implants at their site of performance, following minimally invasive surgical procedures. Aiming at combining syringability and enhanced mechanical properties, a new family of injectable RTG-displaying polymers...

journal_title：Biomacromolecules

authors： Cohn D,Sosnik A,Garty S

更新日期：2005-05-01 00:00:00

abstract：:The SEC-MALS-QELS (size-exclusion chromatography equipped with multiangle light scattering and quasi-elastic light scattering detectors) method using lithium chloride/N,N-dimethylacetamide (LiCl/DMAc) and LiCl/1,3-dimethyl-2-imidazolidinone (LiCl/DMI) as mobile phases was applied to cellulose and cellulose tricarbanil...

journal_title：Biomacromolecules

authors： Yanagisawa M,Isogai A

更新日期：2005-05-01 00:00:00

abstract：:Ozonolysis of methyl soyate (biodiesel) was conducted in the presence of methanol, dichloromethane (solvent), and triethylamine (catalyst) at -75 degrees C. Structural analysis, including FTIR, GC, and GC-MS, showed that the total amount of double bonds in the mixture was reduced by more than 90% after 2 h of ozonolys...

journal_title：Biomacromolecules

authors： Baber TM,Graiver D,Lira CT,Narayan R

更新日期：2005-05-01 00:00:00

abstract：:Trimethylsilylation of chitin was studied in detail to establish a reliable method, and the properties of the resulting product were elucidated. Chitin was successfully trimethylsilylated with a mixture of hexamethyldisilazane and trimethylsilyl chloride in pyridine. Compared to alpha-chitin, beta-chitin was much more...

journal_title：Biomacromolecules

authors： Kurita K,Sugita K,Kodaira N,Hirakawa M,Yang J

更新日期：2005-05-01 00:00:00

abstract：:We report the preparation, characterization, and mechanical properties of DNA/poly(allylamine hydrochloride) (PAH) multilayer microcapsules. The DNA/PAH multilayers were first constructed on a planar support to examine their layer-by-layer buildup. Surface plasmon resonance spectroscopy (SPR) showed a nonlinear growth...

journal_title：Biomacromolecules

authors： Vinogradova OI,Lebedeva OV,Vasilev K,Gong H,Garcia-Turiel J,Kim BS

更新日期：2005-05-01 00:00:00

abstract：:Bovine serum albumin (BSA) and poly(diallyldimethylammonium chloride) (PDADMAC) spontaneously form, over a range of ionic strength I and pH, dense fluids rich in both macroions. To study their nanostructure, these coacervates were prepared at low I and high pH (strong interaction) or at high I and lower pH (weaker int...

journal_title：Biomacromolecules

authors： Bohidar H,Dubin PL,Majhi PR,Tribet C,Jaeger W

更新日期：2005-05-01 00:00:00

abstract：:Methylprednisolone steroid esters of hyaluronan differing in degree of functionalization and molecular weight were investigated in aqueous solution. Conformation and aggregation phenomena were elucidated by means of circular dichroism, viscometry, rheology, and nuclear magnetic resonance, mainly by (1)H pulsed field g...

journal_title：Biomacromolecules

authors： Taglienti A,Valentini M,Sequi P,Crescenzi V

更新日期：2005-05-01 00:00:00

abstract：:This study clarifies the contribution to overall osmotic kinetics of colloid osmotic pressure (Pi) and the interaction of synthetic colloids with the membrane. Solutions (6%) of dextran with weight average molecular weight (MW(w)) 68 800 (DEX 70), dextran with MW(w) 40 000 (DEX 40), hydroxyethyl starch with MW(w) 70 0...

journal_title：Biomacromolecules

authors： Tatara T,Tashiro C

更新日期：2005-05-01 00:00:00

abstract：:Nowadays the open and the patent literatures propose a large number of polymers whose main chains can be degraded usefully. Among these degradable polymers, aliphatic polyester-based polymeric structures are receiving special attention because they are all more or less sensitive to hydrolytic degradation, a feature of...

journal_title：Biomacromolecules

authors： Vert M

更新日期：2005-03-01 00:00:00

abstract：:We have constructed a tandem gene expression cassette containing three Ralstonia eutropha poly[(R)-3-hydroxybutyrate] (PHB) synthesis genes under the control of the Pichia pastoris glyceraldehyde-3-phosphate promoter and the green fluorescent protein (Gfp) under the control of the P. pastoris alcohol oxidase promoter....

journal_title：Biomacromolecules

authors： Vijayasankaran N,Carlson R,Srienc F

更新日期：2005-03-01 00:00:00

abstract：:Hemicellulose-based hydrogels were prepared by radical polymerization of 2-hydroxyethyl methacrylate or poly(ethylene glycol) dimethacrylate with oligomeric hydrosoluble hemicellulose modified with well-defined amounts of methacrylic functions. The polymerization reaction was carried out in water at 40 degrees C using...

journal_title：Biomacromolecules

authors： Söderqvist Lindblad M,Albertsson AC,Ranucci E,Laus M,Giani E

更新日期：2005-03-01 00:00:00

abstract：:Coniferyl alcohol was polymerized in pectin solution in order to mimic the lignification that is the final step of biosynthesis of plant cell wall. Dehydrogenated polymers (DHP = coniferyl alcohol polymers = synthetic lignin) interact with pectin to form hydrophobic clusters as monitored by pyrene fluorescence spectro...

journal_title：Biomacromolecules

authors： Lairez D,Cathala B,Monties B,Bedos-Belval F,Duran H,Gorrichon L

更新日期：2005-03-01 00:00:00

abstract：:The polarity of polymer-actin complexes obtained by mixing F-actin with synthetic polymers carrying positive charges such as poly(L-lysine), x,y-ionene bromide polymers, and poly(N-[3-(dimethylamino)propyl]acrylamide) (PDMAPAA-Q) have been investigated. Actin complexes formed with poly(L-lysine) and PDMAPAA-Q, which c...

journal_title：Biomacromolecules

authors： Kakugo A,Shikinaka K,Takekawa N,Sugimoto S,Osada Y,Gong JP

更新日期：2005-03-01 00:00:00

abstract：:Water soluble polymer anticancer conjugates can improve the pharmacokinetics of covalently bound drugs by limiting cellular uptake to the endocytic route, thus prolonging plasma circulation time and consequently facilitating tumor targeting by the enhanced permeability and retention (EPR) effect. Many of the first gen...

journal_title：Biomacromolecules

authors： Andersson L,Davies J,Duncan R,Ferruti P,Ford J,Kneller S,Mendichi R,Pasut G,Schiavon O,Summerford C,Tirk A,Veronese FM,Vincenzi V,Wu G

更新日期：2005-03-01 00:00:00

abstract：:The synthesis of biocompatible, thermo-responsive ABA triblock copolymers in which the outer A blocks comprise poly(N-isopropylacrylamide) and the central B block is poly(2-methacryloyloxyethyl phosphorylcholine) is achieved using atom transfer radical polymerization with a commercially available bifunctional initiato...

journal_title：Biomacromolecules

authors： Li C,Tang Y,Armes SP,Morris CJ,Rose SF,Lloyd AW,Lewis AL

更新日期：2005-03-01 00:00:00

abstract：:This paper reports the synthesis of hyaluronan (HA) and its derivatives via the hyaluronidase-catalyzed polymerization of 2-substituted oxazoline derivative monomers designed as "transition-state analogue substrates". Polymerization of 2-methyl oxazoline monomer from N-acetylhyalobiuronate (GlcAbeta(1-->3)GlcNAc) effe...

journal_title：Biomacromolecules

authors： Ochiai H,Ohmae M,Mori T,Kobayashi S

更新日期：2005-03-01 00:00:00

abstract：:Glycerol derivatives of cutin and suberin monomers were synthesized by acid catalysis. Their dispersion in an aqueous solution was examined by phase contrast microscopy, neutron scattering, and solid state NMR. It is shown that the phase behavior strongly depends on the nature of the derivatives forming either lumps o...

journal_title：Biomacromolecules

authors： Douliez JP,Barrault J,Jerome F,Heredia A,Navailles L,Nallet F

更新日期：2005-01-01 00:00:00

abstract：:The structure of an extracellular polysaccharide (EPS) from Streptococcus thermophilus THS has been determined. A combination of component analysis, methylation analysis and NMR spectroscopy shows that the polysaccharide is composed of pentasaccharide repeating units. Sequential information was obtained by two-dimensi...

journal_title：Biomacromolecules

authors： Nordmark EL,Yang Z,Huttunen E,Widmalm G

更新日期：2005-01-01 00:00:00

abstract：:The copper(II) complex formation equilibria of N-(2-carboxyethyl)chitosans with three different degrees of substitution (DS = 0.42, 0.92, and 1.61) were studied in aqueous solution by pH-potentiometric and UV-spectrophotometric techniques. It was demonstrated that the complexation model of CE-chitosans depends on DS: ...

journal_title：Biomacromolecules

authors： Skorik YA,Gomes CA,Podberezskaya NV,Romanenko GV,Pinto LF,Yatluk YG

更新日期：2005-01-01 00:00:00

abstract：:The main objective of the present work was the development of new nanoparticulate carrier systems for the delivery of plasmid DNA. These new carriers consist of a blend matrix formed by a poly(lactic-co-glycolic acid) (PLGA) copolymer and polyoxyethylene derivatives. More specifically, we have prepared nanostructures ...

journal_title：Biomacromolecules

authors： Csaba N,Caamaño P,Sánchez A,Domínguez F,Alonso MJ

更新日期：2005-01-01 00:00:00

abstract：:This paper describes the synthesis and cytotoxicity of poly(anhydride esters) that are composed of several salicylate derivatives, including halogenated salicylates, aminosalicylates, salicylsalicylic acid, and thiolsalicylic acid. The incorporation of these nonsteroidal antiinflammatory drugs (NSAIDs) into a biodegra...

journal_title：Biomacromolecules

authors： Schmeltzer RC,Schmalenberg KE,Uhrich KE

更新日期：2005-01-01 00:00:00

abstract：:Sequential copolymerizations of trimethylene carbonate (TMC) and l-lactide (LLA) were performed with 2,2-dibutyl-2-stanna-1,3-oxepane as a bifunctional cyclic initiator. The block lengths were varied via the monomer/initiator and via the TMC/l-lactide ratio. The cyclic triblock copolymers were transformed in situ into...

journal_title：Biomacromolecules

authors： Pospiech D,Komber H,Jehnichen D,Häussler L,Eckstein K,Scheibner H,Janke A,Kricheldorf HR,Petermann O

更新日期：2005-01-01 00:00:00

abstract：:A novel methacrylate monomer containing a quinolone moiety was synthesized and homopolymerized in N,N-dimethylformamide (DMF) by using azobisisobutyronitrile (AIBN) as an initiator. The new monomer was copolymerized with poly(ethylene glycol) methyl ether methacrylate (MPEGMA) in DMF using the same initiator. The mono...

journal_title：Biomacromolecules

authors： Dizman B,Elasri MO,Mathias LJ

更新日期：2005-01-01 00:00:00

abstract：:A novel family of amphiphilic temperature- and pH-sensitive poly(organophosphazenes) with varying ratios of ethylene oxide, alkyl chains and free acid units was synthesized by living cationic polymerization. Depending on their composition, these poly(organophosphazenes) exhibited lower critical solution temperatures r...

journal_title：Biomacromolecules

authors： Couffin-Hoarau AC,Leroux JC

更新日期：2004-11-01 00:00:00

abstract：:The objective of this study is to investigate the influence of point mutations on the structural stability of coiled coil fragments of the human hair intermediate filament by molecular dynamics simulations and free energy calculations. Mutations in the helix termination motif of human hair keratin gene hHb6 seem to be...

journal_title：Biomacromolecules

authors： Danciulescu C,Nick B,Wortmann FJ

更新日期：2004-11-01 00:00:00

abstract：:In a previous study, we have reported chemical synthesis of novel aliphatic poly(butylene succinate-co-cyclic carbonate) P(BS-co-CC)s bearing various functionalizable carbonate building blocks, and this work will continue to present our new studies on their enzymatic degradation and in vitro cell biocompatibility assa...

journal_title：Biomacromolecules

authors： Yang J,Tian W,Li Q,Li Y,Cao A

更新日期：2004-11-01 00:00:00

abstract：:Gold nanoparticles were prepared by reducing gold salt with a polysaccharide, chitosan, in the absence/presence of tripolyphosphate (TPP). Here, chitosan acted as a reducing/stabilizing agent. The obtained gold nanoparticles were characterized with UV--vis spectroscopy and transmission electron microscopy. The results...

journal_title：Biomacromolecules

authors： Huang H,Yang X

更新日期：2004-11-01 00:00:00

abstract：:Oscillatory shear rheometry has been used to study the gelation of beta-lactoglobulin at ambient in 50% v/v trifluoroethanol (TFE)/pH 7 aqueous buffer and in 50% v/v ethanol (EtOH)/water at pH 2. In contrast to what was found on heating aqueous solutions at pH 2 (Part 2 of this series), a more expected "chemical gelat...

journal_title：Biomacromolecules

authors： Gosal WS,Clark AH,Ross-Murphy SB

更新日期：2004-11-01 00:00:00

abstract：:Block copolypeptides, which combine the self-assembly of block copolymers and the highly ordered 3D structures of proteins, are potential candidates for novel supramolecular structures and biotech applications, such as biosensors, tissue engineering, and selective drug delivery. The synthesis of model block copolypept...

journal_title：Biomacromolecules

authors： Aliferis T,Iatrou H,Hadjichristidis N

更新日期：2004-09-01 00:00:00

abstract：:The mechanical rigidity and degradation rate of hydrogels utilized as cell transplantation vehicles have been regarded as critical factors in new tissue formation. However, conventional approaches to accelerate the degradation rate of gels deteriorate their function as a mechanical support in parallel. We hypothesized...

journal_title：Biomacromolecules

authors： Kong HJ,Kaigler D,Kim K,Mooney DJ

更新日期：2004-09-01 00:00:00

abstract：:Inulin, the polydisperse polyfructose, extracted from chicory, has been modified via transesterification, using fatty acid methyl esters (FAME). The grafting of an alkyl chain onto the inulin backbone under different conditions for the development of potential tensio-active derivatives is described. The modification o...

journal_title：Biomacromolecules

authors： Rogge TM,Stevens CV

更新日期：2004-09-01 00:00:00

abstract：:Previously, we have shown that the amphiphilic decyl esters of both D- and L-tyrosine (DELT) self-assemble in aqueous solution above their critical micelle concentration values to form long rodlike structures that can be enzymatically polymerized. In the current study, we have examined the self-assembled structures of...

journal_title：Biomacromolecules

authors： Marx KA,Lee JS,Sung C

更新日期：2004-09-01 00:00:00

abstract：:Photoexcited TiO2 degrades biomolecules such as nucleic acids, cell membrane proteins, and enzymes. Stabilization of enzyme activity against the deactivation caused by the combination of TiO2-UV is essential if we are to develop novel hybrid materials exhibiting photocatalytic and biocatalytic activities useful for de...

journal_title：Biomacromolecules

authors： Lele BS,Russell AJ

更新日期：2004-09-01 00:00:00

abstract：:A successful strategy for the immobilization of rennet from Mucor miehei has been developed. The strategy is based on the immobilization of the enzyme, via their sugar chains at high ionic strength on aminated supports having primary amino groups with a very low pK value. The rennet was covalently immobilized via suga...

journal_title：Biomacromolecules

authors： Pessela BC,Torres R,Fuentes M,Mateo C,Fernandez-Lafuente R,Guisán JM

更新日期：2004-09-01 00:00:00

abstract：:Cross-linked homopolymers and copolymers of 2-hydroxyethyl methacrylate, HEMA, and ethylene glycol methacrylate phosphate, MOEP, have been synthesized, and the diffusion of water into these systems has been investigated. Only polymers with 0-20 mol % MOEP exhibited ideal swelling behavior as extensive fracturing occur...

journal_title：Biomacromolecules

authors： George KA,Wentrup-Byrne E,Hill DJ,Whittaker AK

更新日期：2004-07-01 00:00:00

abstract：:Fibrin sealants are a type of soft tissue adhesive that employs biochemical reactions from the late stages of the blood coagulation cascade. Intrinsic to these adhesives are a structural protein and a transglutaminase crosslinking enzyme. We are investigating an alternative biomimetic adhesive based on gelatin and a c...

journal_title：Biomacromolecules

authors： McDermott MK,Chen T,Williams CM,Markley KM,Payne GF

更新日期：2004-07-01 00:00:00

abstract：:In marine mussels (Mytilus), byssal threads are made in minutes from prefabricated smectic polymer liquid crystals by a process resembling reaction injection molding. The mesogens in these arrays are known to be natural block copolymers with rodlike collagen cores. Using atomic force microscopy, it was shown that thes...

journal_title：Biomacromolecules

authors： Hassenkam T,Gutsmann T,Hansma P,Sagert J,Waite JH

更新日期：2004-07-01 00:00:00